Transportan 10 improves the anticancer activity of cisplatin
نویسندگان
چکیده
منابع مشابه
Protein and siRNA delivery by transportan and transportan 10 into colorectal cancer cell lines.
INTRODUCTION Cell penetrating peptides (CPPs) have the ability to translocate through cell membranes with high efficiency and therefore can introduce biological agents with pharmaceutical properties into the cell. Transportan (TP) and its shorter analog transportan 10 (TP10) are among the best studied CPPs, however, their effects on viability of and cargo introduction into colorectal cancer (CR...
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In this study, the ability of nanocarriers containing protein transduction domains (PTDs) of various classes to improve cutaneous paclitaxel delivery and efficacy in skin tumor models was evaluated. Microemulsions (MEs) were prepared by mixing a surfactant blend (polyoxyethylene 10 oleoyl ether, ethanol and propylene glycol), monocaprylin, and water. The PTD transportan (ME-T), penetratin (ME-P...
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ژورنال
عنوان ژورنال: Naunyn-Schmiedeberg's Archives of Pharmacology
سال: 2016
ISSN: 0028-1298,1432-1912
DOI: 10.1007/s00210-016-1219-5